The Effect of Kaka Bitters on the Lipidprofile of Wistar Rats Fed With High Fatdiet
Content Structure of The Effect of Kaka Bitters on the Lipidprofile of Wistar Rats Fed With High Fatdiet
The abstract contains the research problem, the objectives, methodology, results, and recommendations
- Chapter one of this thesis or project materials contains the background to the study, the research problem, the research questions, research objectives, research hypotheses, significance of the study, the scope of the study, organization of the study, and the operational definition of terms.
- Chapter two contains relevant literature on the issue under investigation. The chapter is divided into five parts which are the conceptual review, theoretical review, empirical review, conceptual framework, and gaps in research
- Chapter three contains the research design, study area, population, sample size and sampling technique, validity, reliability, source of data, operationalization of variables, research models, and data analysis method
- Chapter four contains the data analysis and the discussion of the findings
- Chapter five contains the summary of findings, conclusions, recommendations, contributions to knowledge, and recommendations for further studies.
- References: The references are in APA
Introduction Of The Effect of Kaka Bitters on the Lipidprofile of Wistar Rats Fed With High Fatdiet
Kaka bitters like other bitters is claimed to possess a number of folkloric therapeutic effects including lipid-lowering effects. However, there is no scientific data available as at the time of this study to evidence this claim. The Lipid-lowering effects of Kaka bitters were investigated by assessing it effects on the blood lipid parameters of wistar rats fed fat-enhanced diet. The was divided into three (3) groups: Group 1 rats was fed normal feed with distilled water; Group 2 was fed fat-enhanced diet with distilled water and Group 3 was fed fat-enhanced diet with Kaka bitters. The result obtained shows that blood TG levels decreased in group 3 rats compared with group 2, but the decrease is not statistically significant (p < 0.05). Also there was a statistically significant decrease in blood HDL levels and also statistically significant increase in total cholesterol and LDL levels of group 3 rats compared with group 2 (p < 0.05). The hyperlipidemic effect of Kaka bitters indicated by this result may be due to the alcoholic nature of Kaka bitters coupled with the antimicrobial effect of the bitters against the gut microbiota implicated in cholesterol metabolism and excretion. Kaka bitters is not a good therapy for treatment of dyslipidemia.