Medicine Project Topics

Effects of Heavy Metal on Human Respiratory System

Effects of Heavy Metal on Human Respiratory System


Effects of Heavy Metal on Human Respiratory System


Content Structure of Effects of Heavy Metal on Human Respiratory System

  • The abstract contains the research problem, the objectives, methodology, results, and recommendations
  • Chapter one of this thesis or project materials contains the background to the study, the research problem, the research questions, research objectives, research hypotheses, significance of the study, the scope of the study, organization of the study, and the operational definition of terms.
  • Chapter two contains relevant literature on the issue under investigation. The chapter is divided into five parts which are the conceptual review, theoretical review, empirical review, conceptual framework, and gaps in research
  • Chapter three contains the research design, study area, population, sample size and sampling technique, validity, reliability, source of data, operationalization of variables, research models, and data analysis method
  • Chapter four contains the data analysis and the discussion of the findings
  • Chapter five contains the summary of findings, conclusions, recommendations, contributions to knowledge, and recommendations for further studies.
  • References: The references are in APA
  • Questionnaire


Chapter One of Effects of Heavy Metal on Human Respiratory System




  Heavy metals include both non-toxic and toxic elements. Iron (Fe), Cobalt (Co) Copper (Cu) Manganese (Mn) Molybdenum (Mo) and Zinc (Zc) Magnesium(Mg) are the trace elements and are required in a very minute amount, whereas other metals are non-essential, toxic to animals and even fatal when accumulated these metals includes; Mercury (Hg), Arsenic (As), Lead (Pb) Plutonium (Pu), Vanadium (v), Tungsten (w) and Cadmium (Cd), (Deevikaet al., 2012).

  Heavy metals with established toxic action to humans include cadmium (Morrow, 2010 and Hayes, 2007) lead (Eric, 2013 and Patrick, 2006 and mercury (Bojorklund, 1995).Each of these has been studied in isolation for toxicity (Morrow, 2010; Patrick,2006 and Clarkson, and Magoss. 2006). But in the ecosystem, be it air, (atmosphere, land and water) where they occur they do not exist in isolation. They occur in close association with other metal and non-metallic elemental pollutants. Among the metallic pollutant could be calcium, copper, zinc, magnesium, manganese, iron and others. Metals are known to interact with one another. Interaction can bring about two element together include proximately and could cause out right displacement with one another. When ingested in food and water they can antagonize each other. When it comes to intestinal hand and pulmonary absorption it is there   conceivable that the presence of other element can affect the toxic potential of each of the heavy metal that has been study in isolation.

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Egborge (1994) reported that Warri River had and unacceptability high cadmium level, 0.3mg/l of H2O, was 60-fold above the maximal allowable level of 0.005mg/l. This report prompted our early studies on the hepato-, nephro-  and  goladal toxicity  of cadmium in rat expose to this high close via water and diet. The diet was formulated with fish expose to 0.3mgCd/water in the ambient water, as protein source and the toxic effects investigated and reported. (Asagba and Obi, 2000; Asagba and Obi, 2001; Obi and Ilori, 2002; Asagba and Obi, 2004a; Asagba and Obi, 2004b; Asagba and Obi, 2005). The  studies focus on cadmium without taken into consideration the fact that other metal were also present the river water and as such were co-consumed by the communities using the river water for cooking  drinking and other domestic purposes. Hence it is desirable to know if the presence of other metal would enhance or diminish the toxic potential of cadmium or indeed that of any other metal such as lead that was mention above. Therefore the aim of this present studies was to re-examine the toxic potential of cadmium in the presence of other metals such as magnesium.  The objective set out to achieve were:

v Re-examination of the kidney toxicity of cadmium using established toxicity index for kidney such as Creatinine, Blood urea nitrogen and Alkaline phosphatase.

v Re-examine the status of the parameters in the absence of cadmium but in the presence of magnesium.

v Re-examine this parameterin the presence of cadmium and magnesium.

Download Chapters 1 to 5 PDF         



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